Water → Hydroxy-[2-(4-methoxy-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-acetic acid ethyl ester

HRID 1226447Notes

Reaction equation

HRID 1226447 reaction equation
[C:26]([CH:27]=[O:28])(=[O:29])[O:30][CH2:31][CH3:32].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]3[n:12]([cH:13][c:14]([CH3:17])[cH:15][cH:16]3)[cH:18]2)[cH:7][cH:8]1.[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[OH2:33].[c:19]1([CH3:20])[cH:21][cH:22][cH:23][cH:24][cH:25]1.[c:34]1([CH3:35])[cH:36][cH:37][c:38]([S:39]([OH:40])(=[O:41])=[O:42])[cH:43][cH:44]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]3[n:12]([cH:13][c:14]([CH3:17])[cH:15][cH:16]3)[c:18]2[CH:27]([C:26](=[O:29])[O:30][CH2:31][CH3:32])[OH:28])[cH:7][cH:8]1

Participants

6

Reactant 5

HCID 962WaterHCID 1140Toluene2×HCID 6101p-Toluenesulfonic acidHCID 70211Ethyl oxoacetateHCID 7359102-(4-Methoxyphenyl)-6-methylimidazo[1,2-a]pyridine

Product 1

HCID 58763627Hydroxy-[2-(4-methoxy-phenyl)-6-methyl-imidazo[1,2-a]pyridin-3-yl]-acetic acid ethyl ester

Sources & evidence

ORD record
ord-e59caf76bee9447f81e4973c743425b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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