Dimethylformamide → 4-Chloro-6,7,8-trimethoxy-3-quinolinecarbonitrile

HRID 1226784Notes

Reaction equation

HRID 1226784 reaction equation
[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[OH:1][c:2]1[c:3]([C:18]#[N:19])[cH:4][n:5][c:6]2[c:7]([O:16][CH3:17])[c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[P:20]([Cl:21])([Cl:22])([Cl:23])=[O:24]>>[c:2]1([Cl:22])[c:3]([C:18]#[N:19])[cH:4][n:5][c:6]2[c:7]([O:16][CH3:17])[c:8]([O:14][CH3:15])[c:9]([O:12][CH3:13])[cH:10][c:11]12

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 178486763HCID 178486763, compound

Product 1

HCID 224666114-Chloro-6,7,8-trimethoxy-3-quinolinecarbonitrile

Sources & evidence

ORD record
ord-261b3d9748e04b04908f97585791b303
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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