Dimethylformamide → 3-bromo-2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole

HRID 1226891Notes

Reaction equation

HRID 1226891 reaction equation
[Br:19][NH:20][C:21](=[O:22])[CH2:23][CH2:24][C:25]([NH2:26])=[O:27].[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6](-[c:8]2[c:9]([C:16]([OH:17])=[O:18])[c:10]3[n:11]([n:12]2)[CH2:13][CH2:14][CH2:15]3)[n:7]1.[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38]>>[CH3:1][c:2]1[cH:3][cH:4][cH:5][c:6](-[c:8]2[c:9]([Br:19])[c:10]3[n:11]([n:12]2)[CH2:13][CH2:14][CH2:15]3)[n:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9834204N-BromosuccinamideHCID 219925742-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid

Product 1

HCID 99002873-bromo-2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole

Sources & evidence

ORD record
ord-8dbf4f95d9d844c2bc6400cab9a92f7b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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