Dimethylformamide → 1'-{[1-(4-hydroxyphenyl)cyclopropyl]carbonyl}-3H-spiro[furo[3,4-c]pyridine-1,3'-pyrrolidin]-3-one
Reaction equation
[CH3:41][N:42]([CH3:43])[CH:44]=[O:45].[CH:60]([N:61]([CH2:62][CH3:63])[CH:64]([CH3:65])[CH3:66])([CH3:67])[CH3:68].[NH:46]1[CH2:47][C:48]2([O:49][C:50](=[O:57])[c:51]3[cH:52][n:53][cH:54][cH:55][c:56]32)[CH2:58][CH2:59]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[OH:13])[CH2:9][CH2:10]2)[cH:6][cH:7]1.[P-:14]([F:15])([F:16])([F:17])([F:18])([F:19])[F:20].[n:21]1([O:22][P+:23]([N:24]([CH3:25])[CH3:26])([N:27]([CH3:28])[CH3:29])[N:30]([CH3:31])[CH3:32])[c:33]2[cH:34][cH:35][cH:36][cH:37][c:38]2[n:39][n:40]1>>[OH:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:13])[N:46]3[CH2:47][C:48]4([O:49][C:50](=[O:57])[c:51]5[cH:52][n:53][cH:54][cH:55][c:56]54)[CH2:58][CH2:59]3)[CH2:9][CH2:10]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-541f82d0c579409abc6e0a5a826e1a9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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