Dimethylformamide → (2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)-(3-fluorophenyl)-amine

HRID 1226963Notes

Reaction equation

HRID 1226963 reaction equation
[CH3:29][N:30]([CH3:31])[CH:32]=[O:33].[CH:12]([N:13]([CH:14]([CH3:15])[CH3:16])[CH2:17][CH3:18])([CH3:19])[CH3:20].[Cl:1][c:2]1[n:3][c:4]([Cl:11])[c:5]2[c:6]([n:7]1)[CH2:8][CH2:9][S:10]2.[F:21][c:22]1[cH:23][c:24]([NH2:28])[cH:25][cH:26][cH:27]1>>[Cl:1][c:2]1[n:3][c:4]([NH:28][c:24]2[cH:23][c:22]([F:21])[cH:27][cH:26][cH:25]2)[c:5]2[c:6]([n:7]1)[CH2:8][CH2:9][S:10]2

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 97423-FluoroanilineHCID 81531DiisopropylethylamineHCID 457899672,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine

Product 1

HCID 59708433(2-Chloro-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)-(3-fluorophenyl)-amine

Sources & evidence

ORD record
ord-66a481404ed2416d8f5376b6e70c9e7e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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