Dimethylformamide → 1-Isopropyl-4-(4-nitrophenyl)piperazine

HRID 122698Notes

Reaction equation

HRID 122698 reaction equation
[CH:11]([N:12]([CH2:13][CH3:14])[CH:15]([CH3:16])[CH3:17])([CH3:18])[CH3:19].[CH:20]([CH3:21])([CH3:22])[N:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1.[F:1][c:2]1[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[c:2]1([N:26]2[CH2:25][CH2:24][N:23]([CH:20]([CH3:21])[CH3:22])[CH2:28][CH2:27]2)[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 9590p-FluoronitrobenzeneHCID 780131-IsopropylpiperazineHCID 81531Diisopropylethylamine

Product 1

HCID 98347891-Isopropyl-4-(4-nitrophenyl)piperazine

Sources & evidence

ORD record
ord-622dd7cae3f74f00919f33c79d223afa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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