Imidazole → 2-[4-(Tert-butyldimethylsilanyloxy)-3-chlorophenyl]acetamide
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[Si:22]([CH3:23])([CH3:24])[Cl:25].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[Cl:1][c:2]1[cH:3][c:4]([CH2:9][C:10](=[O:11])[NH2:12])[cH:5][cH:6][c:7]1[OH:8].[nH:13]1[cH:14][cH:15][n:16][cH:17]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:9][C:10](=[O:11])[NH2:12])[cH:5][cH:6][c:7]1[O:8][Si:22]([C:18]([CH3:19])([CH3:20])[CH3:21])([CH3:23])[CH3:24]Participants
6
Sources & evidence
- ORD record
- ord-eeafba21470e48b3b382f1448a2dad7d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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