Water → Tert-butyl 3-{[1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-(dimethylamino)-2-oxoethyl]amino}propylcarbamate
Reaction equation
[C:32](=[O:33])([O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[NH:39][CH2:40][CH2:41][CH2:42][NH2:43].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH:20]([C:21](=[O:22])[N:23]([CH3:24])[CH3:25])[Br:26])[n:10][c:11]2[cH:12][c:13]([Cl:19])[cH:14][cH:15][c:16]2[c:17]1=[O:18].[CH3:27][N:28]([CH3:29])[CH:30]=[O:31].[CH3:45][CH2:46][O:47][C:48](=[O:49])[CH3:50].[OH2:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH:20]([C:21](=[O:22])[N:23]([CH3:24])[CH3:25])[NH:43][CH2:42][CH2:41][CH2:40][NH:39][C:32](=[O:33])[O:34][C:35]([CH3:36])([CH3:37])[CH3:38])[n:10][c:11]2[cH:12][c:13]([Cl:19])[cH:14][cH:15][c:16]2[c:17]1=[O:18]Participants
6
Sources & evidence
- ORD record
- ord-dddbbcba0ac64778ba82cbcb0663da08
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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