Tetrahydrofuran → HCID 22379891, compound

HRID 1228019Notes

Reaction equation

HRID 1228019 reaction equation
[Br:19][c:20]1[cH:21][c:22]2[c:23]([n:24]([CH2:29][CH3:30])[c:25]([CH2:27][Cl:28])[n:26]2)[cH:31][cH:32]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:12][CH:13]([N-:14][CH:15]([CH3:16])[CH3:17])[CH3:18].[F:1][c:2]1[cH:3][c:4]([C:8]([CH3:9])=[O:10])[cH:5][cH:6][cH:7]1.[Li+:11]>>[F:1][c:2]1[cH:3][c:4]([C:8]([CH2:9][CH2:27][c:25]2[n:24]([CH2:29][CH3:30])[c:23]3[c:22]([cH:21][c:20]([Br:19])[cH:32][cH:31]3)[n:26]2)=[O:10])[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 99673-FluoroacetophenoneHCID 28486Lithium ionHCID 5062348DiisopropylamideHCID 22379875HCID 22379875, compound

Product 1

HCID 22379891HCID 22379891, compound

Sources & evidence

ORD record
ord-1481e76300b545629357970d98753422
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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