Diethyl Ether → 3-[3-oxo-7-[[3-[[2-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[1,5-a]pyrazin-7-yl]methyl]phenyl]methoxy]-1H-isoindol-2-yl]piperidine-2,6-dione
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][c:5]([CH2:6][O:7][c:8]2[c:9]3[c:13]([cH:14][cH:15][cH:16]2)[C:12](=[O:17])[N:11]([CH:18]2[C:19](=[O:25])[NH:20][C:21](=[O:24])[CH2:22][CH2:23]2)[CH2:10]3)[cH:26][cH:27][cH:28]1.[CH3:54][CH2:55][O:56][C:57]([CH3:58])=[O:59].[CH3:60][CH2:61][O:62][CH2:63][CH3:64].[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[Cl:51][CH2:52][Cl:53].[F:29][C:30]([c:31]1[n:32][n:33]2[c:34]([n:39]1)[CH2:35][NH:36][CH2:37][CH2:38]2)([F:40])[F:41]>>[CH2:2]([c:3]1[cH:4][c:5]([CH2:6][O:7][c:8]2[c:9]3[c:13]([cH:14][cH:15][cH:16]2)[C:12](=[O:17])[N:11]([CH:18]2[C:19](=[O:25])[NH:20][C:21](=[O:24])[CH2:22][CH2:23]2)[CH2:10]3)[cH:26][cH:27][cH:28]1)[N:36]1[CH2:35][c:34]2[n:33]([n:32][c:31]([C:30]([F:29])([F:40])[F:41])[n:39]2)[CH2:38][CH2:37]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-49e4509d8eea48aa8f7bea7c24fc75e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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