Dimethylformamide → 4-[3-(dimethylamino)prop-1-ynyl]-5-fluoro-3-[(5-methyl-1H-imidazol-4-yl)methylidene]-1H-indol-2-one
Reaction equation
[CH3:1][N:2]([CH3:3])[CH2:4][C:5]#[CH:6].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[F:7][c:8]1[c:9]([I:25])[c:10]2[c:14]([cH:15][cH:16]1)[NH:13][C:12](=[O:17])[C:11]2=[CH:18][c:19]1[c:20]([CH3:24])[n:21][cH:22][nH:23]1.[O:26]=[CH:27][N:28]([CH3:29])[CH3:30]>>[CH3:1][N:2]([CH3:3])[CH2:4][C:5]#[C:6][c:9]1[c:8]([F:7])[cH:16][cH:15][c:14]2[c:10]1[C:11](=[CH:18][c:19]1[c:20]([CH3:24])[n:21][cH:22][nH:23]1)[C:12](=[O:17])[NH:13]2Participants
5
Sources & evidence
- ORD record
- ord-8c95da6eca0145bbb0054c4f2a19e8b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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