Imidazole → 3-[(2,6-Dichloro-4-phenylmethoxyphenyl)methyl]-1-[4-tri(propan-2-yl)silyloxycyclohexyl]pyrrolidin-2-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:30])[c:12]([CH2:13][CH:14]2[C:15](=[O:26])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:27]([Cl:29])[cH:28]1.[CH:36]([CH3:37])([CH3:38])[Si:39]([CH:40]([CH3:41])[CH3:42])([CH:43]([CH3:44])[CH3:45])[Cl:46].[O:47]=[CH:48][N:49]([CH3:50])[CH3:51].[nH:31]1[cH:32][cH:33][n:34][cH:35]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:30])[c:12]([CH2:13][CH:14]2[C:15](=[O:26])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([O:25][Si:39]([CH:36]([CH3:37])[CH3:38])([CH:40]([CH3:41])[CH3:42])[CH:43]([CH3:44])[CH3:45])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:27]([Cl:29])[cH:28]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-86fe82c9bb1f4d25a8d9d610bc488e62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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