Chloroacetyl chloride → N-[3-({2-[(chloroacetyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-3-(1-cyanocyclopropyl)benzamide
Reaction equation
[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cl:39][CH2:40][C:41](=[O:42])[Cl:43].[NH2:1][c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18]([c:19]4[cH:20][c:21]([C:25]5([C:28]#[N:29])[CH2:26][CH2:27]5)[cH:22][cH:23][cH:24]4)=[O:30])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:31]1.[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[NH:1]([c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([O:10][c:11]3[cH:12][c:13]([NH:17][C:18]([c:19]4[cH:20][c:21]([C:25]5([C:28]#[N:29])[CH2:26][CH2:27]5)[cH:22][cH:23][cH:24]4)=[O:30])[cH:14][cH:15][cH:16]3)[cH:8][cH:9]2)[cH:31]1)[C:41]([CH2:40][Cl:39])=[O:42]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-cd292addbcfc46e2901b243c59b66fa6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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