1-Butanol → 4-Amino-N-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

HRID 1229720Notes

Reaction equation

HRID 1229720 reaction equation
[CH2:38]([OH:39])[CH2:40][CH2:41][CH3:42].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:21][c:22]1[c:23]2[c:24]([n:25][cH:26][n:27]1)[nH:28][cH:29][cH:30]2.[Cl:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][NH:9][C:10](=[O:11])[C:12]2([NH2:18])[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:19][cH:20]1.[ClH:1].[ClH:2]>>[Cl:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][NH:9][C:10](=[O:11])[C:12]2([NH2:18])[CH2:13][CH2:14][N:15]([c:22]3[c:23]4[c:24]([n:25][cH:26][n:27]3)[nH:28][cH:29][cH:30]4)[CH2:16][CH2:17]2)[cH:19][cH:20]1

Participants

6

Reactant 5

HCID 2631-ButanolHCID 313Hydrochloric Acid2×HCID 8471TriethylamineHCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-HCID 451396224-Amino-N-(4-chlorobenzyl)piperidine-4-carboxamide

Product 1

HCID 116753884-Amino-N-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

Sources & evidence

ORD record
ord-1b5ba9db246e4d6594efec4f09faa54d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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