Acetate → 3-(Tridec-1-yn-1-yl)pyridine-4-carbaldehyde

HRID 1229853Notes

Reaction equation

[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[CH:8]=[O:9].[C:49]([O-:50])(=[O:51])[CH3:52].[C:54]([O-:55])(=[O:56])[CH3:57].[CH3:42][CH2:43][N:44]([CH2:45][CH3:46])[CH2:47][CH3:48].[CH:10]#[C:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22].[Pd+2:53].[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[c:2]1([C:10]#[C:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[cH:3][n:4][cH:5][cH:6][c:7]1[CH:8]=[O:9]

Participants

Reactant 6

HCID 175Acetate2×

HCID 8471Triethylamine

HCID 11776Triphenylphosphine

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 1177541-Tridecyne

HCID 27629973-Bromopyridine-4-carboxaldehyde

Product 1

HCID 201471503-(Tridec-1-yn-1-yl)pyridine-4-carbaldehyde

Sources & evidence

ORD record: ord-5a93921b1238474daf335274a2e051c2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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