1,2-Dichloroethane → 6-bromo-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-1H-indole-4-carboxamide

HRID 1229967Notes

Reaction equation

HRID 1229967 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:14](=[O:15])[OH:16])[c:5]2[cH:6][cH:7][n:8]([CH:11]([CH3:12])[CH3:13])[c:9]2[cH:10]1.[CH2:38]([Cl:39])[CH2:40][Cl:41].[CH3:42][N:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1.[CH3:49][S:50]([CH3:51])=[O:52].[NH2:17][CH2:18][c:19]1[c:20](=[O:27])[nH:21][c:22]([CH3:26])[cH:23][c:24]1[CH3:25].[OH:28][n:29]1[c:30]2[n:31][cH:32][cH:33][cH:34][c:35]2[n:36][n:37]1>>[Br:1][c:2]1[cH:3][c:4]([C:14](=[O:16])[NH:17][CH2:18][c:19]2[c:20](=[O:27])[nH:21][c:22]([CH3:26])[cH:23][c:24]2[CH3:25])[c:5]2[cH:6][cH:7][n:8]([CH:11]([CH3:12])[CH3:13])[c:9]2[cH:10]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 679Dimethyl SulfoxideHCID 79724-MethylmorpholineHCID 181649HOAtHCID 70638443-(Aminomethyl)-4,6-dimethyl-1,2-dihydropyridin-2-oneHCID 674686386-bromo-1-(1-methylethyl)-1H-indole-4-carboxylic acid

Product 1

HCID 546701646-bromo-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-1H-indole-4-carboxamide

Sources & evidence

ORD record
ord-c8cf072bbc82474b9afbe81398ee840f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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