Tetrahydrofuran → 2-(2-Mercaptoethyl)-piperidine-1-carboxylic acid benzyl ester

HRID 1230278Notes

Reaction equation

HRID 1230278 reaction equation
[C:53]([OH:54])(=[S:55])[CH3:56].[CH2:34]([c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1)[O:41][C:42](=[O:43])[N:44]1[CH:45]([CH2:50][CH2:51][OH:52])[CH2:46][CH2:47][CH2:48][CH2:49]1.[O:20]=[C:21]([O:22][CH:23]([CH3:24])[CH3:25])[N:26]=[N:27][C:28]([O:29][CH:30]([CH3:31])[CH3:32])=[O:33].[O:57]1[CH2:58][CH2:59][CH2:60][CH2:61]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH2:34]([c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1)[O:41][C:42](=[O:43])[N:44]1[CH:45]([CH2:50][CH2:51][SH:55])[CH2:46][CH2:47][CH2:48][CH2:49]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 45358666Benzyl 2-(2-hydroxyethyl)piperidine-1-carboxylateHCID 178418634HCID 178418634, compound

Product 1

HCID 543726122-(2-Mercaptoethyl)-piperidine-1-carboxylic acid benzyl ester

Sources & evidence

ORD record
ord-8aca57ad1acd44b38bcf3c032fa53630
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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