Dichloromethane → [6-(2,3-difluorophenyl)-9-tri(propan-2-yl)silyloxy-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-yl] acetate
Reaction equation
[CH2:46]([Cl:47])[Cl:48].[CH3:32][C:33](=[O:34])[O:35][C:36](=[O:37])[CH3:38].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[CH3:49][N:50]([c:51]1[cH:52][cH:53][n:54][cH:55][cH:56]1)[CH3:57].[F:1][c:2]1[c:3]([CH:9]2[CH:10]([OH:31])[c:11]3[c:12]([n:13][cH:14][cH:15][cH:16]3)[CH:17]([O:20][Si:21]([CH:22]([CH3:23])[CH3:24])([CH:25]([CH3:26])[CH3:27])[CH:28]([CH3:29])[CH3:30])[CH2:18][CH2:19]2)[cH:4][cH:5][cH:6][c:7]1[F:8]>>[F:1][c:2]1[c:3]([CH:9]2[CH:10]([O:31][C:33]([CH3:32])=[O:34])[c:11]3[c:12]([n:13][cH:14][cH:15][cH:16]3)[CH:17]([O:20][Si:21]([CH:22]([CH3:23])[CH3:24])([CH:25]([CH3:26])[CH3:27])[CH:28]([CH3:29])[CH3:30])[CH2:18][CH2:19]2)[cH:4][cH:5][cH:6][c:7]1[F:8]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-04443fa6fa184ff4a6a4fd11ab112552
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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