Hydrochloric Acid → 4-Bromo-3-fluoro-N-methoxy-N-methylbenzamide

HRID 1230750Notes

Reaction equation

HRID 1230750 reaction equation
[Br:7][c:8]1[c:9]([F:17])[cH:10][c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16]1.[C:23](=[O:24])([O-:25])[O-:26].[CH3:19][NH:20][O:21][CH3:22].[Cl:1][C:2]([C:3]([Cl:4])=[O:5])=[O:6].[Cl:29][CH2:30][Cl:31].[ClH:18].[K+:27].[K+:28].[OH2:32]>>[Br:7][c:8]1[c:9]([F:17])[cH:10][c:11]([C:12](=[O:13])[N:20]([CH3:19])[O:21][CH3:22])[cH:15][cH:16]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 14232N,O-DimethylhydroxylamineHCID 19660Carbonate IonHCID 65578Oxalyl chlorideHCID 27733414-Bromo-3-fluorobenzoic acid

Product 1

HCID 223138234-Bromo-3-fluoro-N-methoxy-N-methylbenzamide

Sources & evidence

ORD record
ord-94b735945156488cae64f3681763bb8d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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