Potassium Cation → N-[3-ethyl-4-[7-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-pyrrolo[2,3-h][1,6]naphthyridin-1-yl]cyclopentyl]cyclopropanesulfonamide

HRID 123179Notes

Reaction equation

HRID 123179 reaction equation
[CH2:50]([OH:51])[CH2:52][CH3:53].[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[CH2:8][CH2:9][CH2:10][NH:11][CH:12]1[CH2:13][CH:14]([NH:19][S:20](=[O:21])(=[O:22])[CH:23]3[CH2:24][CH2:25]3)[CH2:15][CH:16]1[CH2:17][CH3:18])[n:26]([S:29](=[O:30])(=[O:31])[c:32]1[cH:33][cH:34][c:35]([CH3:36])[cH:37][cH:38]1)[cH:27][cH:28]2.[I-:49].[K+:48]>>[c:2]12[c:3]3[c:4]([n:5][cH:6][c:7]1[CH2:8][CH2:9][CH2:10][N:11]2[CH:12]1[CH2:13][CH:14]([NH:19][S:20](=[O:21])(=[O:22])[CH:23]2[CH2:24][CH2:25]2)[CH2:15][CH:16]1[CH2:17][CH3:18])[n:26]([S:29](=[O:30])(=[O:31])[c:32]1[cH:33][cH:34][c:35]([CH3:36])[cH:37][cH:38]1)[cH:27][cH:28]3

Participants

6

Reactant 5

HCID 813Potassium CationHCID 10311-PropanolHCID 30165Iodide IonHCID 81531DiisopropylethylamineHCID 76829111N-[3-[3-[4-chloro-1-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyridin-5-yl]propylamino]-4-ethylcyclopentyl]cyclopropanesulfonamide

Product 1

HCID 76828962N-[3-ethyl-4-[7-(4-methylphenyl)sulfonyl-3,4-dihydro-2H-pyrrolo[2,3-h][1,6]naphthyridin-1-yl]cyclopentyl]cyclopropanesulfonamide

Sources & evidence

ORD record
ord-61ec86eb54f24d7da72e16d243c06373
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…