Tetrahydrofuran → 3-(7-methoxy-2,2-dimethyl-4-oxo-1,2,3,4-tetrahydro-naphthalen-1-yl)-3H-imidazole-4-carboxylic acid isopropyl ester

HRID 1232438Notes

Reaction equation

HRID 1232438 reaction equation
[CH2:57]1[O:58][CH2:59][CH2:60][CH2:61]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[C:9](=[O:13])[CH2:8][C:7]([CH3:14])([CH3:15])[CH:6]2[OH:16].[N:47]([C:48]([O:49][CH3:50])=[O:51])=[N:52][C:53]([O:54][CH3:55])=[O:56].[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1.[nH:17]1[cH:18][n:19][c:20]([C:22](=[O:23])[O:24][CH:25]([CH3:26])[CH3:27])[cH:21]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[C:9](=[O:13])[CH2:8][C:7]([CH3:14])([CH3:15])[CH:6]2[n:19]1[cH:18][n:17][cH:21][c:20]1[C:22](=[O:23])[O:24][CH:25]([CH3:26])[CH3:27]

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 351621Azodicarboxylic acid dimethyl esterHCID 675467026-methoxy-4-hydroxy-3,3-dimethyl-3,4-dihydro-2H-naphthalen-1-oneHCID 178459416HCID 178459416, compound

Product 1

HCID 591993943-(7-methoxy-2,2-dimethyl-4-oxo-1,2,3,4-tetrahydro-naphthalen-1-yl)-3H-imidazole-4-carboxylic acid isopropyl ester

Sources & evidence

ORD record
ord-6d680c051d8d4cf193d45a522a504959
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…