Dimethylformamide → 4-Methyl-2-pyridin-2-yl-pyrimidine-5-carboxylic acid (5-methoxy-3-methyl-pyrrolo[3,2-b]pyridin-1-yl)-amide

HRID 1232925Notes

Reaction equation

HRID 1232925 reaction equation
[CH3:17][O:18][c:19]1[cH:20][cH:21][c:22]2[c:23]([n:24]1)[c:25]([CH3:29])[cH:26][n:27]2[NH2:28].[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[O:63]=[CH:64][N:65]([CH3:66])[CH3:67].[P-:39]([F:40])([F:41])([F:42])([F:43])([F:44])[F:45].[n:1]1[c:2](-[c:7]2[n:8][cH:9][c:10]([C:14](=[O:15])[OH:16])[c:11]([CH3:13])[n:12]2)[cH:3][cH:4][cH:5][cH:6]1.[n:46]1([O:47][C:48]([N:49]([CH3:50])[CH3:51])=[N+:52]([CH3:53])[CH3:54])[c:55]2[n:56][cH:57][cH:58][cH:59][c:60]2[n:61][n:62]1>>[n:1]1[c:2](-[c:7]2[n:8][cH:9][c:10]([C:14](=[O:16])[NH:28][n:27]3[c:22]4[cH:21][cH:20][c:19]([O:18][CH3:17])[n:24][c:23]4[c:25]([CH3:29])[cH:26]3)[c:11]([CH3:13])[n:12]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 617020254-Methyl-2-(pyridin-2-yl)pyrimidine-5-carboxylic acidHCID 685551495-Methoxy-3-methyl-pyrrolo[3,2-b]pyridin-1-ylamine

Product 1

HCID 592000424-Methyl-2-pyridin-2-yl-pyrimidine-5-carboxylic acid (5-methoxy-3-methyl-pyrrolo[3,2-b]pyridin-1-yl)-amide

Sources & evidence

ORD record
ord-588d3d6e388e4b158479f6bd23ab95f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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