Toluene → 2-tert-Butyl-4-chloro-6-cyclopropyl-pyrimidine

HRID 1233711Notes

Reaction equation

HRID 1233711 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([CH:12]2[CH2:13][CH2:14]2)[cH:8][c:9]([OH:11])[n:10]1.[CH3:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[CH3:27][N:28]([CH3:29])[CH:30]=[O:31].[P:15]([Cl:16])([Cl:17])([Cl:18])=[O:19]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([CH:12]2[CH2:13][CH2:14]2)[cH:8][c:9]([Cl:17])[n:10]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 178441865HCID 178441865, compound

Product 1

HCID 633553042-tert-Butyl-4-chloro-6-cyclopropyl-pyrimidine

Sources & evidence

ORD record
ord-35938a6490f4467ea125bd734aa0fba2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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