Sodium ion → Methyl 4-(7-iodo-6-oxo-1,2,3,4,7,8,9,9a-octahydroquinolizin-4-yl)benzoate

HRID 1234198Notes

Reaction equation

HRID 1234198 reaction equation
[C:6](=[O:7])([O:8][CH3:9])[c:10]1[cH:11][cH:12][c:13]([CH:16]2[N:17]3[C:18](=[O:26])[CH2:19][CH2:20][CH2:21][CH:22]3[CH2:23][CH2:24][CH2:25]2)[cH:14][cH:15]1.[CH2:43]([Cl:44])[Cl:45].[CH3:27][N:28]([CH3:29])[CH2:30][CH2:31][N:32]([CH3:33])[CH3:34].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[I:1][Si:2]([CH3:3])([CH3:4])[CH3:5].[I:35].[Na+:41].[Na+:42].[S:36]([O-:37])([O-:38])(=[O:39])=[S:40]>>[I:1][CH:19]1[C:18](=[O:26])[N:17]2[CH:16]([c:13]3[cH:12][cH:11][c:10]([C:6](=[O:7])[O:8][CH3:9])[cH:15][cH:14]3)[CH2:25][CH2:24][CH2:23][CH:22]2[CH2:21][CH2:20]1

Participants

9

Reactant 8

HCID 923Sodium ion2×HCID 1084Thiosulfate ionHCID 6344DichloromethaneHCID 8037N,N,N',N'-TetramethylethylenediamineHCID 8857Ethyl AcetateHCID 24841Hydrogen iodideHCID 85247Trimethylsilyl iodideHCID 69070571HCID 69070571, compound

Product 1

HCID 69072715Methyl 4-(7-iodo-6-oxo-1,2,3,4,7,8,9,9a-octahydroquinolizin-4-yl)benzoate

Sources & evidence

ORD record
ord-99ee67254fea4768847b17804f5414ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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