Methyl iodide → 4-(4-cyano-2-ethylsulfonylphenyl)-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4H-pyrimidine-5-carbonitrile
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([S:29](=[O:30])(=[O:31])[CH2:32][CH3:33])[c:6]([CH:9]2[NH:10][C:11](=[O:28])[N:12]([c:18]3[cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[cH:21][cH:22][cH:23]3)[C:13]([CH3:17])=[C:14]2[C:15]#[N:16])[cH:7][cH:8]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:34][Si:35]([CH3:36])([CH3:37])[N-:38][Si:39]([CH3:40])([CH3:41])[CH3:42].[I:44][CH3:45].[Li+:43]>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([S:29](=[O:30])(=[O:31])[CH2:32][CH3:33])[c:6]([CH:9]2[N:10]([CH3:34])[C:11](=[O:28])[N:12]([c:18]3[cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[cH:21][cH:22][cH:23]3)[C:13]([CH3:17])=[C:14]2[C:15]#[N:16])[cH:7][cH:8]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f91022a83106405097e225860bafef34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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