Methanol → (4-Bromo-2,6-dimethylphenyl)-[4-[2-(hydroxymethyl)pyrrolidin-1-yl]piperidin-1-yl]methanone
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:32])[c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][CH:11]([N:14]3[CH:15]([CH2:19][O:20][C:21](=[O:22])[c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:16][CH2:17][CH2:18]3)[CH2:12][CH2:13]2)[c:29]([CH3:31])[cH:30]1.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:40][OH:41].[Li+:33].[OH-:34]>>[Br:1][c:2]1[cH:3][c:4]([CH3:32])[c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][CH:11]([N:14]3[CH:15]([CH2:19][OH:20])[CH2:16][CH2:17][CH2:18]3)[CH2:12][CH2:13]2)[c:29]([CH3:31])[cH:30]1Participants
6
Sources & evidence
- ORD record
- ord-79a354f4ff394e789c1416897f73d6e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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