Methanol → 2-(5-Chloro-6-(cyclopropylmethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-3-cyclopropylpropanoic acid
Reaction equation
[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:36][OH:37].[Cl:1][c:2]1[cH:3][c:4]([CH:23]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:29][CH:30]2[CH2:31][CH2:32]2)[cH:5][c:6](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1.[Li+:35].[OH-:34].[OH2:33].[OH2:43]>>[Cl:1][c:2]1[cH:3][c:4]([CH:23]([C:24](=[O:25])[OH:26])[CH2:29][CH:30]2[CH2:31][CH2:32]2)[cH:5][c:6](-[c:13]2[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:7]1[O:8][CH2:9][CH:10]1[CH2:11][CH2:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-cce47e4d260c4070a2231bcc43de98fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…