Dimethyl Sulfoxide → Tert-butyl 3-oxopiperidine-1-carboxylate

HRID 1235990Notes

Reaction equation

HRID 1235990 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:14])[CH2:11][CH2:12][CH2:13]1.[CH2:36]([N:37]([CH2:38][CH3:39])[CH2:40][CH3:41])[CH3:42].[CH3:15][S:16](=[O:17])[CH3:18].[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[OH2:19].[S:26](=[O:27])(=[O:28])=[O:29].[n:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10](=[O:14])[CH2:11][CH2:12][CH2:13]1

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 1049PyridineHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 24682Sulfur trioxideHCID 5456991-Boc-3-hydroxypiperidine

Product 1

HCID 2756825Tert-butyl 3-oxopiperidine-1-carboxylate

Sources & evidence

ORD record
ord-951a689cc382457289d56d94f08a1229
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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