Hydrochloric Acid → 2-(4-Chloro-phenyl)-6-(4-hydroxy-3-methoxy-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one

HRID 1236164Notes

Reaction equation

HRID 1236164 reaction equation
[CH2:38]([N+:39]([CH2:40][CH2:41][CH2:42][CH3:43])([CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH2:50][CH3:51])[CH2:52][CH2:53][CH3:54].[CH2:56]1[O:57][CH2:58][CH2:59][CH2:60]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([s:36]2)[C:12](=[O:35])[N:13]([c:16]2[cH:17][c:18]([O:33][CH3:34])[c:19]([O:22][Si:23]([CH:24]([CH3:25])[CH3:26])([CH:27]([CH3:28])[CH3:29])[CH:30]([CH3:31])[CH3:32])[cH:20][cH:21]2)[CH2:14][CH2:15]3)[cH:6][cH:7]1.[ClH:55].[F-:37]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([s:36]2)[C:12](=[O:35])[N:13]([c:16]2[cH:17][c:18]([O:33][CH3:34])[c:19]([OH:22])[cH:20][cH:21]2)[CH2:14][CH2:15]3)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 68950353HCID 68950353, compound

Product 1

HCID 689499992-(4-Chloro-phenyl)-6-(4-hydroxy-3-methoxy-phenyl)-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one

Sources & evidence

ORD record
ord-a2e90bc43d3841e58211db7e7ae7761f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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