Hydrochloric Acid → rac-(2S,3R,4S,5R)-4-(3-chloro-2-fluoro-phenyl)-3-(4-chloro-2-fluoro-phenyl)-2-(2,2-dimethyl-propyl)-5-(3-hydroxy-azetidine-1-carbonyl)-pyrrolidine-3-carbonitrile

反応式

[CH:69]([N:70]([CH2:71][CH3:72])[CH:73]([CH3:74])[CH3:75])([CH3:76])[CH3:77].[Cl:78][CH2:79][Cl:80].[Cl:8][c:9]1[c:10]([F:38])[c:11]([CH:15]2[CH:16]([C:35](=[O:36])[OH:37])[NH:17][CH:18]([CH2:30][C:31]([CH3:32])([CH3:33])[CH3:34])[C:19]2([C:20]#[N:21])[c:22]2[c:23]([F:29])[cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[cH:12][cH:13][cH:14]1.[ClH:39].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[NH:40]1[CH2:41][CH:42]([OH:44])[CH2:43]1.[P-:45]([F:46])([F:47])([F:48])([F:49])([F:50])[F:51].[n:52]1([O:53][C:54]([N:55]([CH3:56])[CH3:57])=[N+:58]([CH3:59])[CH3:60])[c:61]2[n:62][cH:63][cH:64][cH:65][c:66]2[n:67][n:68]1>>[Cl:8][c:9]1[c:10]([F:38])[c:11]([CH:15]2[CH:16]([C:35](=[O:37])[N:40]3[CH2:41][CH:42]([OH:44])[CH2:43]3)[NH:17][CH:18]([CH2:30][C:31]([CH3:32])([CH3:33])[CH3:34])[C:19]2([C:20]#[N:21])[c:22]2[c:23]([F:29])[cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[cH:12][cH:13][cH:14]1