Tetrahydrofuran → N-(3-bromophenyl)-7-(1-piperidinylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[c:10]3[c:11]([n:12][cH:13][n:14]2)[s:15][c:16]2[c:17]3[CH2:18][CH2:19][CH:20]([C:22](=[O:23])[N:24]3[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]3)[CH2:21]2)[cH:5][cH:6][cH:7]1.[CH2:31]([Al+:32][CH2:33][CH:34]([CH3:35])[CH3:36])[CH:37]([CH3:38])[CH3:39].[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:40][CH:41]([CH2:42][AlH:43][CH2:44][CH:45]([CH3:46])[CH3:47])[CH3:48].[H-:30]>>[Br:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[c:10]3[c:11]([n:12][cH:13][n:14]2)[s:15][c:16]2[c:17]3[CH2:18][CH2:19][CH:20]([CH2:22][N:24]3[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]3)[CH2:21]2)[cH:5][cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d3b5606dec594b36a6cf729b9d261e26
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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