Ethyl isobutyrate → Ethyl 3-(4-fluorophenyl)-2,2-dimethylpropanoate
Reaction equation
[Br:19][CH2:20][c:21]1[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]1.[C:1]([CH:2]([CH3:3])[CH3:4])(=[O:5])[O:6][CH2:7][CH3:8].[CH3:9][Si:10]([N-:11][Si:12]([CH3:13])([CH3:14])[CH3:15])([CH3:16])[CH3:17].[Li+:18].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[C:1]([C:2]([CH3:3])([CH3:4])[CH2:20][c:21]1[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]1)(=[O:5])[O:6][CH2:7][CH3:8]Participants
6
Sources & evidence
- ORD record
- ord-5ac610f688aa4055bab97f80bd569825
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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