Chloride → 1-Benzyl-4-(4-fluorophenyl)pyrrolidin-3-amine

HRID 1238324Notes

Reaction equation

HRID 1238324 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[CH:11]([N+:13]([O-:14])=[O:15])[CH2:12]1.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:28][CH2:29][O:30][CH2:31][CH3:32].[Cl-:33].[Cl-:35].[Cl-:36].[Cl-:37].[Ti+4:34].[Zn:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[CH:11]([NH2:13])[CH2:12]1

Participants

7

Reactant 6

HCID 312Chloride4×HCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 23994ZincHCID 114942Titanium cation (4+)HCID 66940721rac-(3R,4S)-1-Benzyl-3-(4-fluoro-phenyl)-4-nitro-pyrrolidine

Product 1

HCID 669409261-Benzyl-4-(4-fluorophenyl)pyrrolidin-3-amine

Sources & evidence

ORD record
ord-a967ec9072e7450f986b734b7756d3e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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