Tetrahydrofuran → 2-(2-(t-Butyldimethylsilyloxy)ethyl)-3-phenylpropionitrile
Reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[Si:25]([O:26][CH2:27][CH2:28][I:29])([CH3:30])[CH3:31].[CH3:11][Si:12]([N-:13][Si:14]([CH3:15])([CH3:16])[CH3:17])([CH3:18])[CH3:19].[Li+:20].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[c:1]1([CH2:7][CH2:8][C:9]#[N:10])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][CH:8]([C:9]#[N:10])[CH2:28][CH2:27][O:26][Si:25]([C:21]([CH3:22])([CH3:23])[CH3:24])([CH3:30])[CH3:31])[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
6
Sources & evidence
- ORD record
- ord-0bf6725903b84ae4bc7530eb8e096cc7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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