Hydrochloric Acid → 2-(3,3-Difluoro-3-(4-fluorophenyl)propylthio)-nicotinic acid
Reaction equation
[Br:1][CH2:2][CH2:3][C:4]([F:5])([F:6])[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1.[ClH:30].[K+:14].[K+:15].[O-:16][C:17]([O-:18])=[O:19].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH2:36].[SH:20][c:21]1[c:22]([C:23](=[O:24])[OH:25])[cH:26][cH:27][cH:28][n:29]1>>[CH2:2]([CH2:3][C:4]([F:5])([F:6])[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1)[S:20][c:21]1[c:22]([C:23](=[O:24])[OH:25])[cH:26][cH:27][cH:28][n:29]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-fbc359cb09024ff38d82cd467081d3aa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…