Hydrochloric Acid → 3-(4-Isopropylphenyl)-1',4,6,7-tetramethyl-5-(4-pyridylmethyloxy)spiro[benzofuran-2(3H), 4'-piperidine]
Reaction equation
[CH3:41][N:42]([CH3:43])[CH:44]=[O:45].[CH:3]([CH3:4])([CH3:5])[c:6]1[cH:7][cH:8][c:9]([CH:12]2[C:13]3([O:14][c:15]4[c:16]2[c:17]([CH3:24])[c:18]([OH:23])[c:19]([CH3:22])[c:20]4[CH3:21])[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]3)[cH:10][cH:11]1.[Cl:32][CH2:33][c:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1.[ClH:31].[H-:1].[Na+:2].[OH2:40]>>[CH:3]([CH3:4])([CH3:5])[c:6]1[cH:7][cH:8][c:9]([CH:12]2[C:13]3([O:14][c:15]4[c:16]2[c:17]([CH3:24])[c:18]([O:23][CH2:33][c:34]2[cH:35][cH:36][n:37][cH:38][cH:39]2)[c:19]([CH3:22])[c:20]4[CH3:21])[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]3)[cH:10][cH:11]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-33e8f855ea5344cdaf10e739f81440aa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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