Dimethylformamide → 5-chloro-4-(1-(5-propylpyrimidin-2-yl)piperidin-4-yloxy)pyridin-2(1H)-one
Reaction equation
[C:30](=[O:31])([O-:32])[O-:33].[CH2:1]([CH2:2][CH3:3])[c:4]1[cH:5][n:6][c:7]([N:10]2[CH2:11][CH2:12][CH:13]([CH2:16][S:17]([O-:18])(=[O:19])=[O:20])[CH2:14][CH2:15]2)[n:8][cH:9]1.[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[Cl:21][c:22]1[c:23]([OH:29])[cH:24][c:25](=[O:28])[nH:26][cH:27]1.[Cs+:34].[Cs+:35].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[CH2:1]([CH2:2][CH3:3])[c:4]1[cH:5][n:6][c:7]([N:10]2[CH2:11][CH2:12][CH:13]([O:29][c:23]3[c:22]([Cl:21])[cH:27][nH:26][c:25](=[O:28])[cH:24]3)[CH2:14][CH2:15]2)[n:8][cH:9]1Participants
7
Sources & evidence
- ORD record
- ord-0da90286291748c4b1f522c6bc4f3484
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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