Dichloromethane → Tert-butyl 8-oxa-4-azabicyclo[5.1.0]octane-4-carboxylate

HRID 1238953Notes

Reaction equation

HRID 1238953 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]=[CH:12][CH2:13][CH2:14]1.[CH2:26]([O:27][C:28](=[O:29])[CH3:30])[CH3:31].[Cl:15][c:16]1[cH:17][cH:18][cH:19][c:20]([C:21]([O:22][OH:24])=[O:23])[cH:25]1.[Cl:32][CH2:33][Cl:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]2[CH:12]([CH2:13][CH2:14]1)[O:23]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 70297m-Chloroperbenzoic acidHCID 12969195tert-Butyl 2,3,6,7-tetrahydro-1H-azepine-1-carboxylate

Product 1

HCID 58717040Tert-butyl 8-oxa-4-azabicyclo[5.1.0]octane-4-carboxylate

Sources & evidence

ORD record
ord-7048b7178ec64e63a70927496891fe84
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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