Tetrahydrofuran → Tert-butyl 4-(2-(methylsulfonyloxy)ethyl)piperazine-1-carboxylate

HRID 1239453Notes

Reaction equation

HRID 1239453 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][OH:16])[CH2:12][CH2:13]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:24][S:25]([Cl:26])(=[O:27])=[O:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][O:16][S:25]([CH3:24])(=[O:27])=[O:28])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 735736Tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate

Product 1

HCID 22989493Tert-butyl 4-(2-(methylsulfonyloxy)ethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-27379cf4a3c848bfb295fa1d775c331b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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