Hydrochloric Acid → 5-{[1-(N, N-dimethylglycyl)-3,3-dimethyl-5-(methyloxy)-2,3-dihydro-1H-indol-6-yl]amino}-8-fluoro-3-[(4-methylphenyl)sulfonyl]pyrrolo[2',3':4,5]pyrimido[6,1-b]quinazolin-7(3H)-one
Reaction equation
[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[CH3:32][N:33]([CH3:34])[CH2:35][C:36](=[O:37])[N:38]1[CH2:39][C:40]([CH3:50])([CH3:51])[c:41]2[cH:42][c:43]([O:48][CH3:49])[c:44]([NH2:47])[cH:45][c:46]21.[Cl:2][c:3]1[n:4][c:5]2[c:6]([c:7]3[n:8][c:9]4[cH:10][cH:11][cH:12][c:13]([F:18])[c:14]4[c:15](=[O:17])[n:16]13)[cH:19][cH:20][n:21]2[S:22](=[O:23])(=[O:24])[c:25]1[cH:26][cH:27][c:28]([CH3:31])[cH:29][cH:30]1.[ClH:1]>>[c:3]1([NH:47][c:44]2[c:43]([O:48][CH3:49])[cH:42][c:41]3[c:46]([cH:45]2)[N:38]([C:36]([CH2:35][N:33]([CH3:32])[CH3:34])=[O:37])[CH2:39][C:40]3([CH3:50])[CH3:51])[n:4][c:5]2[c:6]([c:7]3[n:8][c:9]4[cH:10][cH:11][cH:12][c:13]([F:18])[c:14]4[c:15](=[O:17])[n:16]13)[cH:19][cH:20][n:21]2[S:22](=[O:23])(=[O:24])[c:25]1[cH:26][cH:27][c:28]([CH3:31])[cH:29][cH:30]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-8d57174247e94adc86f5fa421eab0920
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…