Hydrochloric Acid → [4-(Tert-butyl-dimethyl-silanyloxy)-indol-1-yl]-acetic acid tert-butyl ester
Reaction equation
[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25]([CH2:26][Br:27])=[O:28].[C:3]([CH3:4])([CH3:5])([CH3:6])[Si:7]([O:8][c:9]1[c:10]2[cH:11][cH:12][nH:13][c:14]2[cH:15][cH:16][cH:17]1)([CH3:18])[CH3:19].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[ClH:29].[H-:1].[Na+:2].[OH2:35]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[Si:7]([O:8][c:9]1[c:10]2[cH:11][cH:12][n:13]([CH2:26][C:25]([O:24][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:28])[c:14]2[cH:15][cH:16][cH:17]1)([CH3:18])[CH3:19]Participants
8
Sources & evidence
- ORD record
- ord-6528518adf0f44878b8f07a2c432436b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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