huagongshe.com
HRID1241499

反应详情

EQUATION

反应方程式

HRID 1241499 的结构方程式

REACTANTS

反应物

2
结构：O=P(Cl)(Cl)Cl
HCID24813

Phosphoric trichloride

Cl3OP

结构：CCC(NC(=O)C1CCC(C(C)(C)C)CC1)c1nnc(C2CCCC2)[nH]c1=O
HCID135594108

未命名化合物

PRODUCTS

生成物

1
结构：CCc1nc(C2CCC(C(C)(C)C)CC2)n2nc(C3CCCC3)[nH]c(=O)c12
HCID135594097

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure for Example 1, 350 mg (0.90 mmol) crude 4-tert-butyl-N-[1-(3-cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]cyclohexanecarboxamide, 140 mg (0.90 mmol) phosphoric trichloride are stirred at reflux for 3 hours, proportionate amounts of the solvents are used. The isomers are separated by chromatography.

WORKUP

后处理

  1. temperatureat reflux for 3 hours
  2. customThe isomers are separated by chromatography