Allyl Isothiocyanate → HCID 21939689, compound

HRID 1242637Notes

Reaction equation

HRID 1242637 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]([NH2:9])[CH2:7][NH2:8].C(N=[C:14]=[S:15])C=C>BrC1C=CC=CC=1>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[CH2:7][NH:8][C:14](=[S:15])[NH:9]1

Participants

4

Reactant 2

HCID 5971Allyl IsothiocyanateHCID 21939690HCID 21939690, compound

Product 1

HCID 21939689HCID 21939689, compoundYield 86.8%

Reagents, catalysts & solvents 1

HCID 7961BromobenzeneSolvent

Procedure

. . A solution of 140 mg (1.0 mmol) of 2-thienyl-1,2-diaminoethane and allyl isothiocyanate (99 mg, 1 mmol) in bromobenzene (5 mL) was heated for 40 min and allowed to cool to room temperature and then cooled to −5° C. The title compound (160 mg, 83% yield) was obtained upon filtration and washing with hexane.

Workup

  1. temperaturecooled to −5° C

Sources & evidence

ORD record
ord-3927865a6d224dd38741e6960fa630da
Source dataset
uspto-grants-2006_10
Patent number
US07115748B2

Reaction notes

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