Methyl 2-[4-benzylpiperazinyl]benzoate → Methyl 2-(piperazin-1-yl)benzoate

HRID 1242724Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1242724
C([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:23]=[CH:22][CH:21]=[CH:20][C:15]=2[C:16]([O:18][CH3:19])=[O:17])[CH2:10][CH2:9]1)C1C=CC=CC=1>[Pd]>[N:11]1([C:14]2[CH:23]=[CH:22][CH:21]=[CH:20][C:15]=2[C:16]([O:18][CH3:19])=[O:17])[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]1

Komponenten

3

Edukt 1

HCID 21935101Methyl 2-[4-benzylpiperazinyl]benzoate

Produkt 1

HCID 10932975Methyl 2-(piperazin-1-yl)benzoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

The title compound was prepared according to the procedure described in Preparation IV by using methyl 2-[4-benzylpiperazinyl]benzoate (2.8 g, 8.9 mmol), 10% Pd/C (Aldrich) (940 mg), and HCO2NH4 (2.8, 44 mmol). The title compound was isolated as a colorless oil (1.75 g). (MS (ESI, pos. ion) m/z: 221 (M+H). Calc'd for C12H16N2O2: 220.12.

Aufarbeitung

  1. customThe title compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-55c106eb892f453d8308f4bfaa0b7ffa
Quelldatensatz
uspto-grants-2006_10
Patentnummer
US07115607B2

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