反应详情

A mixture of 4-bromo-4′-hydroxybiphenyl (50.00 g, 0.2008 mol), 1-bromooctane (50.38 g, 0.2610 mol), potassium carbonate (47.11 g, 0.3414 mol) and butanone (500 cm3) was heated under reflux overnight. The cooled mixture was filtered and the solvent removed on a rotary evaporator. The crude solid was recrystallised from ethanol to yield a white crystalline solid (47.30 g, 66%, m.pt. 120° C.).

1. temperaturewas heated
2. temperatureunder reflux overnight
3. filtrationThe cooled mixture was filtered
4. customthe solvent removed on a rotary evaporator
5. customThe crude solid was recrystallised from ethanol