反应详情

A mixture of 2-bromo-9,9-dioctyl-7-hydroxyfluorene (6.00 g, 0.0124 mol), 1-bromooctane (3.104 g, 0.0161 mol), potassium carbonate (3.41 g, 0.0247 mol) and butanone (100 cm3) was heated under reflux overnight. The cooled mixture was filtered and evaporated down under reduced pressure. The crude product was purified by column chromatography [silica gel, dichloromethane: hexane: 1:1] and then used without further purification (yield 5.04 g, 68.3%), GC: 99%.

1. temperaturewas heated
2. temperatureunder reflux overnight
3. filtrationThe cooled mixture was filtered
4. customevaporated down under reduced pressure
5. customThe crude product was purified by column chromatography [silica gel, dichloromethane: hexane: 1:1]
6. customused without further purification (yield 5.04 g, 68.3%), GC