Benzoyl chloride → HCID 21928838, compound

HRID 1243839Notes

Reaction equation

HRID 1243839 reaction equation
[C:1]1([C:7]2([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH2:15][C:14]3[N:13](S(C4C=CC(C)=CC=4)(=O)=O)[N:12]=[C:11]([NH2:26])[C:10]=3[CH:9]=[CH:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(N(CC)CC)C.[C:40](Cl)(=[O:47])[C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1>ClCCl>[C:1]1([C:7]2([C:27]3[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH2:15][C:14]3[NH:13][N:12]=[C:11]([NH:26][C:40](=[O:47])[C:41]4[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=4)[C:10]=3[CH:9]=[CH:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 7412Benzoyl chlorideHCID 8471TriethylamineHCID 21929019HCID 21929019, compound

Product 1

HCID 21928838HCID 21928838, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

But starting with 0.3 g of 6,6-diphenyl-1-(4-toluenesulphonyl)-6,7-dihydro-1H-indazole-3ylamine, 0.095 cm3 of triethylamine and 0.088 cm3 of benzoyl chloride in cm3 of dichloromethane. After flash chromatography on a column of silica [eluent: dichloromethane], 0.14 g of N-(6,6-diphenyl-6,7-dihydro-1H-indazol-3-yl)benzamide is thus obtained in the form of a foam, the characteristics of which are as follows:

Sources & evidence

ORD record
ord-684d9677a55244e2ac6bbe86f591c6b2
Source dataset
uspto-grants-2006_10
Patent number
US07119115B2

Reaction notes

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