反应详情

Example 109 was prepared from 3-(4-Bromo-phenyl)-4-hydroxy-6-oxo-6,7-dihydro-thieno[2,3-b]pyridine-5-carbonitrile (Example 9) using the same procedure as described for Example 189 substituting 3-thiopheneboronic acid for 4-hydroxyphenyl boronic acid. MS (ESI) m/z 350.9 (M+H+); 1H NMR (300 MHz, DMSO-d6) δ ppm 7.91 (dd, 1H), 7.71 (d, 2H), 7.65 (dd, 1H), 7.60 (dd, 1H), 7.45 (d, 1H).