Potassium Carbonate → HCID 21919275, compound

HRID 1244262Notes

Reaction equation

HRID 1244262 reaction equation
[Cl:1][C:2]1[N:7]=[N:6][C:5]([CH3:8])=[C:4]([CH2:9][CH2:10][CH3:11])[CH:3]=1.C1C=C(Cl)C=C(C(OO)=[O:20])C=1.C([O-])([O-])=O.[K+].[K+]>C(Cl)Cl>[Cl:1][C:2]1[N:7]=[N+:6]([O-:20])[C:5]([CH3:8])=[C:4]([CH2:9][CH2:10][CH3:11])[CH:3]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 219192706-Chloro-3-methyl-4-propylpyridazine

Product 1

HCID 21919275HCID 21919275, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 6-chloro-3-methyl-4-propyl-pyridazine (8.03 g, 47.06 mmol) in CH2Cl2 (200 ml) is added mCPBA (11.6 g, 77%, 51.77 mmol). The mixture is stirred at room temperature overnight. Saturated K2CO3 aqueous solution (50 ml) is added and the layers are separated. The organic layer is then washed with brine (100 ml) and dried (Na2SO4) and evaporated, which provides 6-chloro-3-methyl-4-propyl-pyridazine 2-oxide as a light yellow oil.

Workup

  1. customthe layers are separated
  2. washThe organic layer is then washed with brine (100 ml)
  3. dry with materialdried (Na2SO4)
  4. customevaporated

Sources & evidence

ORD record
ord-7d840d038c98435e86ec8a92807f6a35
Source dataset
uspto-grants-2006_10
Patent number
US07122546B2

Reaction notes

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