反应详情

3-(3,4,5,6-Tetramethoxy-2-methylbenzyl)-2-benzyloxybenzoic acid (652 mg, 1.4424 mmol) was dissolved in methylene chloride (20 ml), then anhydrous methanol (231 mg, 7.2187 mmol), 4-dimethylaminopyridine (264 mg, 2.1639 mmol) and WSC-HCl (830 mg, 4.3296 mmol) were added thereto and the mixture was stirred at room temperature for 16 hours. The reaction solution was washed with water and dried and the solvent was evaporated therefrom. The residue was purified by silica gel column chromatography (hexane:ethyl acetate=4:1) to give the title compound (490 mg, 1.0515 mmol, 73%).

1. washThe reaction solution was washed with water
2. customdried
3. customthe solvent was evaporated
4. customThe residue was purified by silica gel column chromatography (hexane:ethyl acetate=4:1)